POT1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with POT1 polyclonal antibody (Cat # PAB25079).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of POT1.
Immunogen
A synthetic peptide corresponding to POT1.
Host
Rabbit
Theoretical MW (kDa)
72
Reactivity
Human
Specificity
POT1 polyclonal antibody detects endogenous levels of POT1 protein.
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with POT1 polyclonal antibody (Cat # PAB25079). -
Gene Info — POT1
Entrez GeneID
25913Gene Name
POT1
Gene Alias
DKFZp586D211, hPot1
Gene Description
POT1 protection of telomeres 1 homolog (S. pombe)
Omim ID
606478Gene Ontology
HyperlinkGene Summary
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
POT1-like telomere end-binding protein|protection of telomeres 1
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Interactome
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Disease
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