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POT1 polyclonal antibody

  • Catalog # : PAB25079
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of POT1.
  • Immunogen:
  • A synthetic peptide corresponding to POT1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 72
  • Reactivity:
  • Human
  • Specificity:
  • POT1 polyclonal antibody detects endogenous levels of POT1 protein.
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of COS-7 cell lysate with POT1 polyclonal antibody (Cat # PAB25079).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • POT1
  • Gene Alias:
  • DKFZp586D211,hPot1
  • Gene Description:
  • POT1 protection of telomeres 1 homolog (S. pombe)
  • Gene Summary:
  • This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq
  • Other Designations:
  • POT1-like telomere end-binding protein,protection of telomeres 1
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