OPN4 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of COLO 205 cell extracts with OPN4 polyclonal antibody (Cat # PAB25013).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of OPN4.
Immunogen
A synthetic peptide corresponding to OPN4.
Host
Rabbit
Theoretical MW (kDa)
55
Reactivity
Human
Specificity
OPN4 polyclonal antibody detects endogenous levels of OPN4.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COLO 205 cell extracts with OPN4 polyclonal antibody (Cat # PAB25013).Immunofluorescence
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Gene Info — OPN4
Entrez GeneID
94233Gene Name
OPN4
Gene Alias
MGC142118, MOP
Gene Description
opsin 4
Omim ID
606665Gene Ontology
HyperlinkGene Summary
Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000020006|melanopsin
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Disease
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