ST14 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with ST14 polyclonal antibody (Cat # PAB24970) at 1:500 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ST14.
Immunogen
A synthetic peptide corresponding to ST14.
Host
Rabbit
Theoretical MW (kDa)
~90.0
Reactivity
Human
Specificity
ST14 polyclonal antibody detects endogenous levels of ST14 protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with ST14 polyclonal antibody (Cat # PAB24970) at 1:500 dilution.Immunofluorescence
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Gene Info — ST14
Entrez GeneID
6768Gene Name
ST14
Gene Alias
HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15
Gene Description
suppression of tumorigenicity 14 (colon carcinoma)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq
Other Designations
epithin|matriptase|membrane-type serine protease|serine protease TADG-15|suppression of tumorigenicity 14|suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)|tumor associated differentially expressed gene 15 protein
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Interactome
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Disease
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