TNFRSF6B polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TNFRSF6B.
Immunogen
A synthetic peptide corresponding to TNFRSF6B.
Host
Rabbit
Theoretical MW (kDa)
~ 32
Reactivity
Human
Specificity
TNFRSF6B polyclonal antibody detects endogenous levels of TNFRSF6B protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using TNFRSF6B polyclonal antibody (Cat # PAB24965).Immunofluorescence
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Gene Info — TNFRSF6B
Entrez GeneID
8771Gene Name
TNFRSF6B
Gene Alias
DCR3, DJ583P15.1.1, M68, TR6
Gene Description
tumor necrosis factor receptor superfamily, member 6b, decoy
Omim ID
603361Gene Ontology
HyperlinkGene Summary
This gene belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Overexpression of this gene has been noted in gastrointestinal tract tumors, and it is located in a gene-rich cluster on chromosome 20, with other potentially tumor-related genes. Two transcript variants encoding the same isoform, but differing in the 5' UTR, have been observed for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000031583|decoy receptor 3|tumor necrosis factor receptor superfamily, member 6b
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