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Last updated: 2016/12/4
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COL1A2 polyclonal antibody

  • Catalog # : PAB24960
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of COL1A2.
  • Immunogen:
  • A synthetic peptide corresponding to COL1A2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 125
  • Reactivity:
  • Human
  • Specificity:
  • COL1A2 polyclonal antibody detects endogenous levels of COL1A2 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of 293 cell lysate with COL1A2 polyclonal antibody (Cat # PAB24960).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using COL1A2 polyclonal antibody (Cat # PAB24960).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 1278
  • Gene Name:
  • COL1A2
  • Gene Alias:
  • OI4
  • Gene Description:
  • collagen, type I, alpha 2
  • Gene Summary:
  • This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
  • Other Designations:
  • alpha 2 type I collagen,alpha 2(I)-collagen,alpha-2 collagen type I,collagen I, alpha-2 polypeptide,collagen of skin, tendon and bone, alpha-2 chain,type I procollagen
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