RAD51C polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with RAD51C polyclonal antibody (Cat # PAB24950).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RAD51C.
Immunogen
A synthetic peptide corresponding to RAD51C.
Host
Rabbit
Theoretical MW (kDa)
50
Reactivity
Human
Specificity
RAD51C polyclonal antibody detects endogenous levels of RAD51C protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with RAD51C polyclonal antibody (Cat # PAB24950).Immunohistochemistry
Immunofluorescence
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Gene Info — RAD51C
Entrez GeneID
5889Gene Name
RAD51C
Gene Alias
MGC104277, RAD51L2
Gene Description
RAD51 homolog C (S. cerevisiae)
Omim ID
602774Gene Ontology
HyperlinkGene Summary
This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. This gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
DNA repair protein RAD51 homolog 3|RAD51 homolog C|RAD51 homolog C, isoform 1|yeast RAD51 homolog 3
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