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DBI polyclonal antibody

  • Catalog # : PAB24941
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DBI.
  • Immunogen:
  • A synthetic peptide corresponding to DBI.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 10
  • Reactivity:
  • Human
  • Specificity:
  • DBI polyclonal antibody detects endogenous levels of DBI.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HUVEC cell extracts with DBI polyclonal antibody (Cat # PAB24941).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human liver carcinoma tissue with DBI polyclonal antibody (Cat # PAB24941).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1622
  • Gene Name:
  • DBI
  • Gene Alias:
  • ACBD1,ACBP,CCK-RP,EP,MGC70414
  • Gene Description:
  • diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein)
  • Gene Summary:
  • This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • GABA receptor modulator,acyl coenzyme A binding protein,acyl-Coenzyme A binding domain containing 1,cholecystokinin-releasing peptide, trypsin-sensitive,diazepam binding inhibitor,diazepam binding inhibitor, splice form 1c,endozepine
  • Gene Pathway
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