EGFR polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Sheep polyclonal antibody raised against synthetic peptide of EGFR.
Immunogen
A synthetic peptide corresponding to 20 amino acids EGFR.
Host
Sheep
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (10-50 ug/mL)
Immunocytochemistry (25-100 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
Immunoprecipitation (10-12 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
Immunofluorescently labelled cells with EGFR polyclonal antibody (Cat # PAB24933).Immunoprecipitation
-
Gene Info — EGFR
Entrez GeneID
1956Gene Name
EGFR
Gene Alias
ERBB, ERBB1, HER1, PIG61, mENA
Gene Description
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Other Designations
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog|cell growth inhibiting protein 40|cell proliferation-inducing protein 61|epidermal growth factor receptor
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Identification of Active Bronchioalveolar Stem Cells as the Cell-of-Origin in Lung Adenocarcinoma.
Huijing Yin, Bo Jing, Dongliang Xu, Wenzheng Guo, Beibei Sun, Jie Zhang, Yueling Liao, Hongyong Song, Tong Wang, Shuli Liu, Yanbin Kuang, Min Hu, Kaimi Li, Siwei Zhang, Hongjia Zhang, Jianhua Xu, Xue Li, Jing Du, Yadi Wu, Yingli Wu, Qi Wang, Feng Yao, Yueh Eugene Chin, Binhua P Zhou, Jiong Deng.
Cancer Research 2022 Mar; 82(6):1025.
Application:IF, Mouse, Mouse lung.
-
Identification of Active Bronchioalveolar Stem Cells as the Cell-of-Origin in Lung Adenocarcinoma.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com