Western blot analysis of CD247 polyclonal antibody (Cat # PAB2493) in Ramos cell line lysates (35 ug/lane). CD247 (arrow) was detected using the purified polyclonal antibody.
Flow cytometric analysis of Ramos cells using CD247 polyclonal antibody (Cat # PAB2493)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq