MVK polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with MVK polyclonal antibody (Cat # PAB24918).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using MVK polyclonal antibody (Cat # PAB24918).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MVK.
Immunogen
A synthetic peptide corresponding to MVK.
Host
Rabbit
Theoretical MW (kDa)
42
Reactivity
Human
Specificity
MVK polyclonal antibody detects endogenous levels of MVK protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COS-7 cell lysate with MVK polyclonal antibody (Cat # PAB24918).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using MVK polyclonal antibody (Cat # PAB24918).Immunofluorescence
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Gene Info — MVK
Entrez GeneID
4598Gene Name
MVK
Gene Alias
FLJ96772, LRBP, MK, MVLK
Gene Description
mevalonate kinase
Gene Ontology
HyperlinkGene Summary
This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
LH receptor mRNA-binding protein|mevalonic aciduria
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Interactome
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Pathway
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Disease
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