Product Browser

Last updated: 2017/6/25
  • Related Product Showcase
  • By Application

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CYP2A6 polyclonal antibody

  • Catalog # : PAB24904
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYP2A6.
  • Immunogen:
  • A synthetic peptide corresponding to CYP2A6.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 56
  • Reactivity:
  • Human
  • Specificity:
  • CYP2A6 polyclonal antibody detects endogenous levels of CYP2A6 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of Jurkat cell lysate with CYP2A6 polyclonal antibody (Cat # PAB24904).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 1548
  • Gene Name:
  • CYP2A6
  • Gene Alias:
  • CPA6,CYP2A,CYP2A3,P450C2A,P450PB
  • Gene Description:
  • cytochrome P450, family 2, subfamily A, polypeptide 6
  • Gene Summary:
  • This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq
  • Other Designations:
  • coumarin 7-hydroxylase,cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 3,cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6,flavoprotein-linked monooxygenase,xenobiotic monooxygenase
  • RSS
  • YouTube
  • Linkedin
  • Facebook