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Last updated: 2016/10/23
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CYP27A1 polyclonal antibody

  • Catalog # : PAB24903
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYP27A1.
  • Immunogen:
  • A synthetic peptide corresponding to CYP27A1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 60
  • Reactivity:
  • Human
  • Specificity:
  • CYP27A1 polyclonal antibody detects endogenous levels of CYP27A1 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysate with CYP27A1 polyclonal antibody (Cat # PAB24903).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using CYP27A1 polyclonal antibody (Cat # PAB24903).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 1593
  • Gene Name:
  • CYP27A1
  • Gene Alias:
  • CP27,CTX,CYP27
  • Gene Description:
  • cytochrome P450, family 27, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq
  • Other Designations:
  • 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase,5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase,cholestanetriol 26-monooxygenase,cytochrome P-450C27/25,cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrot
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