CYP24A1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with CYP24A1 polyclonal antibody (Cat # PAB24902).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using CYP24A1 polyclonal antibody (Cat # PAB24902).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CYP24A1.
Immunogen
A synthetic peptide corresponding to CYP24A1.
Host
Rabbit
Theoretical MW (kDa)
38
Reactivity
Human
Specificity
CYP24A1 polyclonal antibody detects endogenous levels of CYP24A1 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with CYP24A1 polyclonal antibody (Cat # PAB24902).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using CYP24A1 polyclonal antibody (Cat # PAB24902). -
Gene Info — CYP24A1
Entrez GeneID
1591Gene Name
CYP24A1
Gene Alias
CP24, CYP24, MGC126273, MGC126274, P450-CC24
Gene Description
cytochrome P450, family 24, subfamily A, polypeptide 1
Omim ID
126065Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
1,25-@dihydroxyvitamin D3 24-hydroxylase|24-OHase|OTTHUMP00000031314|cytochrome P450 family 24 subfamily A polypeptide 1|cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)|exo-mitochondrial protein|vitamin D 24-hydroxylase
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Interactome
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Disease
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