TP53I3 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with TP53I3 polyclonal antibody (Cat # PAB24891).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TP53I3.
Immunogen
A synthetic peptide corresponding to TP53I3.
Host
Rabbit
Theoretical MW (kDa)
36
Reactivity
Human
Specificity
TP53I3 polyclonal antibody detects endogenous levels of TP53I3 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with TP53I3 polyclonal antibody (Cat # PAB24891). -
Gene Info — TP53I3
Entrez GeneID
9540Gene Name
TP53I3
Gene Alias
PIG3
Gene Description
tumor protein p53 inducible protein 3
Omim ID
605171Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000116037|p53-induced gene 3 protein|quinone oxidoreductase homolog
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Interactome
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Disease
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