SRY polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with SRY polyclonal antibody (Cat # PAB24884).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SRY.
Immunogen
A synthetic peptide corresponding to SRY.
Host
Rabbit
Theoretical MW (kDa)
37
Reactivity
Human
Specificity
SRY polyclonal antibody detects endogenous levels of SRY protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Purity
> 95% by SDS-PAGE
Recommend Usage
Western Blot (1:500-1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1x PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with SRY polyclonal antibody (Cat # PAB24884).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — SRY
Entrez GeneID
6736Gene Name
SRY
Gene Alias
TDF, TDY
Gene Description
sex determining region Y
Omim ID
480000Gene Ontology
HyperlinkGene Summary
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000034324|essential protein for sex determination in human males|sex determining region protein|sex-determining region on Y|testis-determining factor
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Interactome
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Disease
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