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Last updated: 2016/12/4
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IL10RA polyclonal antibody

  • Catalog # : PAB24859
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IL10RA.
  • Immunogen:
  • A synthetic peptide corresponding to IL10RA.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 63
  • Reactivity:
  • Human
  • Specificity:
  • IL10RA polyclonal antibody detects endogenous levels of IL10RA protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1x PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HepG2 cell lysate with IL10RA polyclonal antibody (Cat # PAB24859).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 3587
  • Gene Name:
  • IL10RA
  • Gene Alias:
  • CDW210A,HIL-10R,IL-10R1,IL10R
  • Gene Description:
  • interleukin 10 receptor, alpha
  • Gene Summary:
  • The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq
  • Other Designations:
  • -
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