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Last updated: 2016/12/4
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SAG polyclonal antibody

  • Catalog # : PAB24838
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SAG.
  • Immunogen:
  • A synthetic peptide corresponding to SAG.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 47
  • Reactivity:
  • Human
  • Specificity:
  • SAG polyclonal antibody detects endogenous levels of SAG protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1x PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human brain tissue using SAG polyclonal antibody (Cat # PAB24838).
  • Immunofluorescence
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 6295
  • Gene Name:
  • SAG
  • Gene Alias:
  • DKFZp686D1084,DKFZp686I1383,S-AG
  • Gene Description:
  • S-antigen; retina and pineal gland (arrestin)
  • Gene Summary:
  • Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq
  • Other Designations:
  • S-arrestin,arrestin 1,retinal S-antigen (48 KDa protein),rod photoreceptor arrestin
  • Related Disease
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