XRCC4 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of XRCC4.
Immunogen
A synthetic peptide corresponding to XRCC4.
Host
Rabbit
Theoretical MW (kDa)
40
Reactivity
Human
Specificity
XRCC4 polyclonal antibody detects endogenous levels of XRCC4 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Purity
> 95% by SDS-PAGE
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1x PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COLO 205 cell lysate with XRCC4 polyclonal antibody (Cat # PAB24836). -
Gene Info — XRCC4
Entrez GeneID
7518Gene Name
XRCC4
Gene Alias
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Gene Description
X-ray repair complementing defective repair in Chinese hamster cells 4
Omim ID
194363Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq
Other Designations
DNA repair protein XRCC4|X-ray repair cross complementing protein 4|X-ray repair, complementing defective, repair in Chinese hamster
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Interactome
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Pathway
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Disease
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