UBA7 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with UBA7 polyclonal antibody (Cat # PAB24833).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using UBA7 polyclonal antibody (Cat # PAB24833).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of UBA7.
Immunogen
A synthetic peptide corresponding to UBA7.
Host
Rabbit
Theoretical MW (kDa)
112
Reactivity
Human
Specificity
UBA7 polyclonal antibody detects endogenous levels of UBA7 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Purity
> 95% by SDS-PAGE
Recommend Usage
Western Blot (1:500-1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1x PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with UBA7 polyclonal antibody (Cat # PAB24833).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using UBA7 polyclonal antibody (Cat # PAB24833). -
Gene Info — UBA7
Entrez GeneID
7318Gene Name
UBA7
Gene Alias
D8, MGC12713, UBA1B, UBE1L, UBE2
Gene Description
ubiquitin-like modifier activating enzyme 7
Omim ID
191325Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq
Other Designations
UBA1, ubiquitin-activating enzyme E1 homolog B|UBA7, ubiquitin-activating enzyme E1|ubiquitin-activating enzyme E1-like|ubiquitin-activating enzyme E1-related protein|ubiquitin-activating enzyme-2
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