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Last updated: 2017/10/22

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CCR5 polyclonal antibody

  • Catalog # : PAB24820
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CCR5.
  • Immunogen:
  • A synthetic peptide corresponding to CCR5.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 50
  • Reactivity:
  • Human
  • Specificity:
  • CCR5 polyclonal antibody detects endogenous levels of CCR5 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1x PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of COS-7 cell lysate with CCR5 polyclonal antibody (Cat # PAB24820).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1234
  • Gene Name:
  • CCR5
  • Gene Alias:
  • CC-CKR-5,CCCKR5,CD195,CKR-5,CKR5,CMKBR5,IDDM22
  • Gene Description:
  • chemokine (C-C motif) receptor 5
  • Gene Summary:
  • This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • C-C chemokine receptor 5,C-C chemokine receptor type 5,CCR5 chemokine receptor,chemokine (C-C) receptor 5,chemokine receptor CCR5,chemr13
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