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Last updated: 2017/8/13
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IAPP polyclonal antibody

  • Catalog # : PAB24819
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of IAPP.
  • Immunogen:
  • A synthetic peptide corresponding to IAPP.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 25
  • Reactivity:
  • Human
  • Specificity:
  • IAPP polyclonal antibody detects endogenous levels of IAPP protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Purity:
  • > 95% by SDS-PAGE
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 1x PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of HeLa cell lysate (treated with EGF 200ng/ml 30min) with IAPP polyclonal antibody (Cat # PAB24819).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human brain tissue using IAPP polyclonal antibody (Cat # PAB24819).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 3375
  • Gene Name:
  • IAPP
  • Gene Alias:
  • AMYLIN,DAP,IAP
  • Gene Description:
  • islet amyloid polypeptide
  • Gene Summary:
  • Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq
  • Other Designations:
  • Islet amyloid polypeptide (diabetes-associated peptide; amylin)
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