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Last updated: 2016/12/4
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FHIT polyclonal antibody

  • Catalog # : PAB24816
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of FHIT.
  • Immunogen:
  • A synthetic peptide corresponding to FHIT.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 16
  • Reactivity:
  • Human
  • Specificity:
  • FHIT polyclonal antibody detects endogenous levels of FHIT protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunohistochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of A-549 cell lysate with FHIT polyclonal antibody (Cat # PAB24816).
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using FHIT polyclonal antibody (Cat # PAB24816).
  • Immunofluorescence
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 2272
  • Gene Name:
  • FHIT
  • Gene Alias:
  • AP3Aase,FRA3B
  • Gene Description:
  • fragile histidine triad gene
  • Gene Summary:
  • This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. [provided by RefSeq
  • Other Designations:
  • AP3A hydrolase,bis(5'-adenosyl)-triphosphatase,diadenosine 5',5'''-P1,P3-triphosphate hydrolase,dinucleosidetriphosphatase,tumor suppressor protein
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