FHIT polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FHIT.
Immunogen
A synthetic peptide corresponding to FHIT.
Host
Rabbit
Theoretical MW (kDa)
16
Reactivity
Human
Specificity
FHIT polyclonal antibody detects endogenous levels of FHIT protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of A-549 cell lysate with FHIT polyclonal antibody (Cat # PAB24816).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using FHIT polyclonal antibody (Cat # PAB24816).Immunofluorescence
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Gene Info — FHIT
Entrez GeneID
2272Gene Name
FHIT
Gene Alias
AP3Aase, FRA3B
Gene Description
fragile histidine triad gene
Omim ID
601153Gene Ontology
HyperlinkGene Summary
This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. [provided by RefSeq
Other Designations
AP3A hydrolase|bis(5'-adenosyl)-triphosphatase|diadenosine 5',5'''-P1,P3-triphosphate hydrolase|dinucleosidetriphosphatase|tumor suppressor protein
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Interactome
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Pathway
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Disease
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