CSE1L polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with CSE1L polyclonal antibody (Cat # PAB24810).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using CSE1L polyclonal antibody (Cat # PAB24810).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CSE1L.
Immunogen
A synthetic peptide corresponding to CSE1L.
Host
Rabbit
Theoretical MW (kDa)
110
Reactivity
Human
Specificity
CSE1L polyclonal antibody detects endogenous levels of CSE1L protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunoprecipitation (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with CSE1L polyclonal antibody (Cat # PAB24810).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human brain tissue using CSE1L polyclonal antibody (Cat # PAB24810).Immunofluorescence
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Gene Info — CSE1L
Entrez GeneID
1434Gene Name
CSE1L
Gene Alias
CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2
Gene Description
CSE1 chromosome segregation 1-like (yeast)
Omim ID
601342Gene Ontology
HyperlinkGene Summary
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq
Other Designations
CSE1 chromosome segregation 1-like protein|OTTHUMP00000043373|cellular apoptosis susceptibility protein|chromosome segregation 1-like|importin-alpha re-exporter
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