BIK polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of A-549 cell lysate with DMSO 0.1% 10' treated. Using BIK polyclonal antibody (Cat # PAB24801).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using BIK polyclonal antibody (Cat # PAB24801).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of BIK.
Immunogen
A synthetic peptide corresponding to BIK.
Host
Rabbit
Theoretical MW (kDa)
23
Reactivity
Human
Specificity
BIK polyclonal antibody detects endogenous levels of BIK protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of A-549 cell lysate with DMSO 0.1% 10' treated. Using BIK polyclonal antibody (Cat # PAB24801).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using BIK polyclonal antibody (Cat # PAB24801).Immunofluorescence
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Gene Info — BIK
Entrez GeneID
638Gene Name
BIK
Gene Alias
BIP1, BP4, NBK
Gene Description
BCL2-interacting killer (apoptosis-inducing)
Omim ID
603392Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. [provided by RefSeq
Other Designations
BCL2-interacting killer|OTTHUMP00000028974|apoptosis-inducing NBK
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Interactome
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Disease
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