ANXA6 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with ANXA6 polyclonal antibody (Cat # PAB24796).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using ANXA6 polyclonal antibody (Cat # PAB24796).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ANXA6.
Immunogen
A synthetic peptide corresponding to ANXA6.
Host
Rabbit
Theoretical MW (kDa)
75
Reactivity
Human
Specificity
ANXA6 polyclonal antibody detects endogenous levels of ANXA6 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of 293 cell lysate with ANXA6 polyclonal antibody (Cat # PAB24796).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using ANXA6 polyclonal antibody (Cat # PAB24796).Immunofluorescence
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Gene Info — ANXA6
Entrez GeneID
309Gene Name
ANXA6
Gene Alias
ANX6, CBP68
Gene Description
annexin A6
Omim ID
114070Gene Ontology
HyperlinkGene Summary
Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. [provided by RefSeq
Other Designations
annexin VI|annexin VI (p68)|calcium-binding protein p68|calelectrin|calphobindin II
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Interactome
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Disease
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