ABCC11 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ABCC11.
Immunogen
A synthetic peptide corresponding to ABCC11.
Host
Rabbit
Theoretical MW (kDa)
23
Reactivity
Human
Specificity
ABCC11 polyclonal antibody detects endogenous levels of ABCC11 protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of A-549 cell lysate with ABCC11 polyclonal antibody (Cat # PAB24793) at 1:500 dilution. -
Gene Info — ABCC11
Entrez GeneID
85320Gene Name
ABCC11
Gene Alias
EWWD, MRP8, WW
Gene Description
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq
Other Designations
ATP-binding cassette protein C11|ATP-binding cassette transporter MRP8|ATP-binding cassette, sub-family C, member 11|OTTHUMP00000164191|multi-resistance protein 8
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Interactome
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Disease
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