CCND3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with CCND3 polyclonal antibody (Cat # PAB24789) at 1:500 dilution.
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CCND3.
Immunogen
A synthetic peptide corresponding to CCND3.
Host
Rabbit
Theoretical MW (kDa)
34.0
Reactivity
Human
Specificity
CCND3 polyclonal antibody detects endogenous levels of CCND3 protein.
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of HeLa cell lysate with CCND3 polyclonal antibody (Cat # PAB24789) at 1:500 dilution. -
Gene Info — CCND3
Entrez GeneID
896Gene Name
CCND3
Gene Alias
-
Gene Description
cyclin D3
Omim ID
123834Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
D3-type cyclin|G1/S-specific cyclin D3|OTTHUMP00000016390
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com