REL polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of MDA-MB-435 cell lysate with REL polyclonal antibody (Cat # PAB24784).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using REL polyclonal antibody (Cat # PAB24784).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of REL.
Immunogen
A synthetic peptide corresponding to REL.
Host
Rabbit
Theoretical MW (kDa)
68
Reactivity
Human
Specificity
REL polyclonal antibody detects endogenous levels of REL protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MDA-MB-435 cell lysate with REL polyclonal antibody (Cat # PAB24784).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using REL polyclonal antibody (Cat # PAB24784). -
Gene Info — REL
Entrez GeneID
5966Gene Name
REL
Gene Alias
C-Rel
Gene Description
v-rel reticuloendotheliosis viral oncogene homolog (avian)
Omim ID
164910Gene Ontology
HyperlinkGene Summary
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM
Other Designations
C-Rel proto-oncogene protein|oncogene REL, avian reticuloendotheliosis|v-rel avian reticuloendotheliosis viral oncogene homolog|v-rel reticuloendotheliosis viral oncogene homolog
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Interactome
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Disease
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