MMP13 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MMP13.
Immunogen
A synthetic peptide corresponding to MMP13.
Host
Rabbit
Theoretical MW (kDa)
55
Reactivity
Human
Specificity
MMP13 polyclonal antibody detects endogenous levels of MMP13 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of LoVo cell lysate with MMP13 polyclonal antibody (Cat # PAB24769).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using MMP13 polyclonal antibody (Cat # PAB24769).Immunofluorescence
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Gene Info — MMP13
Entrez GeneID
4322Gene Name
MMP13
Gene Alias
CLG3
Gene Description
matrix metallopeptidase 13 (collagenase 3)
Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
Other Designations
collagenase 3|matrix metalloproteinase 13|matrix metalloproteinase 13 (collagenase 3)
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Interactome
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Disease
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