SIRT2 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of 293A cell lysate (lane 1) and rat liver (lane 2) tissue lysate with SIRT2 polyclonal antibody (Cat # PAB24745) at 1:1000 dilution.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SIRT2.
Immunogen
A synthetic peptide corresponding to SIRT2.
Host
Rabbit
Theoretical MW (kDa)
42
Reactivity
Human, Rat
Specificity
SIRT2 polyclonal antibody detects endogenous levels of SIRT2 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of 293A cell lysate (lane 1) and rat liver (lane 2) tissue lysate with SIRT2 polyclonal antibody (Cat # PAB24745) at 1:1000 dilution. -
Gene Info — SIRT2
Entrez GeneID
22933Gene Name
SIRT2
Gene Alias
SIR2, SIR2L, SIR2L2
Gene Description
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
Omim ID
604480Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene. [provided by RefSeq
Other Designations
silencing information regulator 2-like|silent information regulator 2|sir2-related protein type 2|sirtuin 2|sirtuin type 2
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