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Last updated: 2017/8/20

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SIRT2 polyclonal antibody

  • Catalog # : PAB24745
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SIRT2.
  • Immunogen:
  • A synthetic peptide corresponding to SIRT2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 42
  • Reactivity:
  • Human, Rat
  • Specificity:
  • SIRT2 polyclonal antibody detects endogenous levels of SIRT2 protein.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of 293A cell lysate (lane 1) and rat liver (lane 2) tissue lysate with SIRT2 polyclonal antibody (Cat # PAB24745) at 1:1000 dilution.
  • Application Image
  • Gene Information
  • Gene Name:
  • SIRT2
  • Gene Alias:
  • SIR2,SIR2L,SIR2L2
  • Gene Description:
  • sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene. [provided by RefSeq
  • Other Designations:
  • silencing information regulator 2-like,silent information regulator 2,sir2-related protein type 2,sirtuin 2,sirtuin type 2
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