TXN polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TXN.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human TXN.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TXN polyclonal antibody (Cat # PAB2465) in HL-60 cell line lysate. TXN (arrow) was detected using the purified polyclonal antibody. -
Gene Info — TXN
Entrez GeneID
7295Protein Accession#
NP_003320;Q5T937Gene Name
TXN
Gene Alias
DKFZp686B1993, MGC61975, TRX, TRX1
Gene Description
thioredoxin
Omim ID
187700Gene Ontology
HyperlinkGene Summary
Thioredoxin is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been identified, including ribonuclease, choriogonadotropins, coagulation factors, glucocorticoid receptor, and insulin. Reduction of insulin is classically used as an activity test.[supplied by OMIM
Other Designations
OTTHUMP00000021892
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Interactome
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Disease
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Publication Reference
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The existence and significance of a mitochondrial nitrite reductase.
Nohl H, Staniek K, Kozlov AV.
Redox Biology 2005 Jul; 10(6):281.
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Direct association of hepatopoietin with thioredoxin constitutes a redox signal transduction in activation of AP-1/NF-kappaB.
Li Y, Liu W, Xing G, Tian C, Zhu Y, He F.
Cellular Signalling 2005 Aug; 17(8):985.
Application:WB-Re, WB-Tr, Monkey, COS-7 cells, Recombinant protein.
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Truncated thioredoxin (Trx80) induces differentiation of human CD14+ monocytes into a novel cell type (TAMs) via activation of the MAP kinases p38, ERK, and JNK.
Pekkari K, Goodarzi MT, Scheynius A, Holmgren A, Avila-Carino J.
Blood 2005 Feb; 105(4):1598.
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The existence and significance of a mitochondrial nitrite reductase.
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