SLC6A3 polyclonal antibody
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Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of SLC6A3.
Immunogen
A synthetic peptide corresponding to near N-terminus of human SLC6A3.
Sequence
C-QLTSSTLTNPRQSP
Host
Goat
Theoretical MW (kDa)
85
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
ELISA (1:4000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
SLC6A3 polyclonal antibody (Cat # PAB24600) (1 ug/mL) staining of human substantia nigra lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC6A3
Entrez GeneID
6531Protein Accession#
NP_001035.1Gene Name
SLC6A3
Gene Alias
DAT, DAT1
Gene Description
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Gene Ontology
HyperlinkGene Summary
The dopamine transporter (DAT1) mediates the active reuptake of dopamine from the synapse and is a principal regulator of dopaminergic neurotransmission. The DAT1 gene has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse (Vandenbergh et al., 1992 [PubMed 1359373]).[supplied by OMIM
Other Designations
dopamine transporter|variable number tandem repeat (VNTR)
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