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CYP2C8 polyclonal antibody

  • Catalog # : PAB24588
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CYP2C8.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human CYP2C8.
  • Sequence:
  • C-KNVALTRSYIREK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 55
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize all reported isoforms (NP_000761.3; NP_001185782.1; NP_001185783.1). No cross-reactivity with other 2C proteins expected. Reported variants represent identical protein: NP_001185782.1, NP_001185784.1
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CYP2C8 polyclonal antibody (Cat # PAB24588) (0.1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1558
  • Protein Accession#:
  • NP_000761.3;NP_001185782.1;NP_001185783.1
  • Gene Name:
  • CYP2C8
  • Gene Alias:
  • CPC8,MP-12/MP-20
  • Gene Description:
  • cytochrome P450, family 2, subfamily C, polypeptide 8
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020134,P450 form 1,cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8,flavoprotein-linked monooxygenase,microsomal monooxygenase,s-mephenytoin 4-hydroxylase,xenobiotic monooxygenase
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