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SLC6A4 polyclonal antibody

  • Catalog # : PAB24582
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of SLC6A4.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 605-618 at C-terminus of human SLC6A4.
  • Sequence:
  • C-KERIIKSITPETPT
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 75
  • Reactivity:
  • Mouse
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • SLC6A4 polyclonal antibody (Cat # PAB24582) (0.5 ug/mL) staining of mouse small intestine lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6532
  • Gene Name:
  • SLC6A4
  • Gene Alias:
  • 5-HTT,5HTT,HTT,OCD1,SERT,hSERT
  • Gene Description:
  • solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Gene Summary:
  • This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq
  • Other Designations:
  • 5-hydroxytryptamine transporter,5HT transporter,Na+/Cl- dependent serotonin transporter,serotonin transporter,sodium-dependent serotonin transporter,solute carrier family 6 member 4
  • Related Disease
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