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Last updated: 2017/9/17

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CHIT1 polyclonal antibody

  • Catalog # : PAB24571
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CHIT1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 409-423 near C-terminus of human CHIT1.
  • Sequence:
  • EHGPSPGQDTFCQGK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 48
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:2000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • CHIT1 polyclonal antibody (Cat # PAB24571) (1 ug/mL) staining of Daudi lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1118
  • Gene Name:
  • CHIT1
  • Gene Alias:
  • CHI3,CHIT,FLJ00314,MGC125322
  • Gene Description:
  • chitinase 1 (chitotriosidase)
  • Gene Summary:
  • Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. [provided by RefSeq
  • Other Designations:
  • chitotriosidase,plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
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