TRIM11 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TRIM11.
Immunogen
A synthetic peptide corresponding to amino acids 249-263 at internal region of human TRIM11.
Sequence
C-DALRRVQDVKLQPPE
Host
Goat
Theoretical MW (kDa)
52
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
ELISA (1:32000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TRIM11 polyclonal antibody (Cat # PAB24564) (0.3 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TRIM11
Entrez GeneID
81559Protein Accession#
NP_660215.1Gene Name
TRIM11
Gene Alias
BIA1, RNF92
Gene Description
tripartite motif-containing 11
Omim ID
607868Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nucleus and the cytoplasm. Its function has not been identified. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple.
Runa Zhang, Si-Wei Li, Lijuan Liu, Jun Yang, Guofu Huang, Yi Sang.
Oncogenesis 2020 May; 9(5):45.
Application:IP, Human, CNE2/DDP cells.
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TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple.
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