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MAPK9 polyclonal antibody

  • Catalog # : PAB24563
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of MAPK9.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 217-230 at internal region of human MAPK9.
  • Sequence:
  • ELVKGCVIFQGTDH
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 48
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoforms alpha1, alpha 2. and gamma (NP_620707.1; NP_002743.3; NP_001128516.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.03-0.1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • MAPK9 polyclonal antibody (Cat # PAB24563) (0.03 ug/mL) staining of HeLa lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5601
  • Protein Accession#:
  • NP_620707.1;NP_002743.3;NP_001128516.1
  • Gene Name:
  • MAPK9
  • Gene Alias:
  • JNK-55,JNK2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,PRKM9,SAPK,p54a,p54aSAPK
  • Gene Description:
  • mitogen-activated protein kinase 9
  • Gene Summary:
  • The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • Jun kinase,MAP kinase 9,c-Jun N-terminal kinase 2,c-Jun kinase 2,mitogen-activated protein kinase 9 isoform JNK2 alpha2,stress-activated protein kinase JNK2
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