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Last updated: 2016/12/4

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TIMP1 polyclonal antibody

  • Catalog # : PAB24555
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of TIMP1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 129-143 at internal region of human TIMP1.
  • Sequence:
  • C-NSLSLAQRRGFTKTY
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 24
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • TIMP1 polyclonal antibody (Cat # PAB24555) (0.1 ug/mL) staining of human kidney lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7076
  • Gene Name:
  • TIMP1
  • Gene Alias:
  • CLGI,EPA,EPO,FLJ90373,HCI,TIMP
  • Gene Description:
  • TIMP metallopeptidase inhibitor 1
  • Gene Summary:
  • This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023214,erythroid potentiating activity,fibroblast collagenase inhibitor,tissue inhibitor of metalloproteinase 1
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