PRODH polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PRODH.
Immunogen
A synthetic peptide corresponding to amino acids 112-134 at internal region of human PRODH.
Sequence
C-EDQESIQPLLRHYR
Host
Goat
Theoretical MW (kDa)
75, 55
Reactivity
Human
Specificity
This antibody is expected to recognize both reported isoforms (NP_057419.4; NP_001182155.1).
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PRODH polyclonal antibody (Cat # PAB24553) (0.3 ug/mL) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PRODH
Entrez GeneID
5625Protein Accession#
NP_057419.4;NP_001182155.1Gene Name
PRODH
Gene Alias
FLJ33744, HSPOX2, MGC148078, MGC148079, PIG6, POX, PRODH1, PRODH2, SCZD4, TP53I6
Gene Description
proline dehydrogenase (oxidase) 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000196495|proline dehydrogenase 1|proline oxidase 2|proline oxidase, mitochondrial|tumor protein p53 inducible protein 6
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Interactome
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Pathway
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Disease
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