TASP1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of TASP1 polyclonal antibody (Cat # PAB2454) in mouse kidney tissue lysates. TASP1 (arrow) was detected using the purified polyclonal antibody .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with TASP1 polyclonal antibody (Cat # PAB2454) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TASP1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human TASP1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TASP1 polyclonal antibody (Cat # PAB2454) in mouse kidney tissue lysates. TASP1 (arrow) was detected using the purified polyclonal antibody .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with TASP1 polyclonal antibody (Cat # PAB2454) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. -
Gene Info — TASP1
Entrez GeneID
55617Protein Accession#
NP_060184;Q9H6P5Gene Name
TASP1
Gene Alias
C20orf13, FLJ20212, MGC39159, dJ585I14.2
Gene Description
taspase, threonine aspartase, 1
Omim ID
608270Gene Ontology
HyperlinkGene Summary
This gene encodes an endopeptidase that cleaves specific substrates following aspartate residues. The encoded protein undergoes posttranslational autoproteolytic processing to generate alpha and beta subunits, which reassemble into the active alpha2-beta2 heterotetramer. It is required to cleave MLL, a protein required for the maintenance of HOX gene expression, and TFIIA, a basal transcription factor. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000030296|taspase 1|threonine aspartase 1
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Interactome
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Publication Reference
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Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression.
Hsieh JJ, Cheng EH, Korsmeyer SJ.
Cell 2003 Oct; 115(3):293.
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Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression.
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