Products

Western Blot (Transfected lysate)

Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate).
Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with MRPL20 polyclonal antibody (Cat # PAB24526).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunohistochemical staining of human colon with MRPL20 polyclonal antibody (Cat # PAB24526) shows strong cytoplasmic positivity in glandular cells at 1:50-1:200 dilution.

Entrez GeneID

55052

Protein Accession#

Q9BYC9

Gene Name

MRPL20

Gene Alias

L20mt, MGC4779, MGC74465, MRP-L20

Gene Description

mitochondrial ribosomal protein L20

Gene Ontology

Hyperlink

Gene Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. [provided by RefSeq

Other Designations

39S ribosomal protein L20, mitochondrial|OTTHUMP00000002947