HNRNPAB polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of HNRNPAB polyclonal antibody (Cat # PAB24511).
Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: human plasma, Lane 4: liver, Lane 5: tonsil.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human uterus, post-menopause with HNRNPAB polyclonal antibody (Cat # PAB24511) shows strong nuclear positivity in glandular cells at 1:20-1:50 dilution.
Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.
Using HNRNPAB polyclonal antibody (Cat # PAB24511).
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant HNRNPAB.
Immunogen
Recombinant protein corresponding to amino acids of human HNRNPAB.
Sequence
MSEAGEEQPMETTGATENGHEAV
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:20-1:50)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of HNRNPAB polyclonal antibody (Cat # PAB24511).
Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: human plasma, Lane 4: liver, Lane 5: tonsil.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human uterus, post-menopause with HNRNPAB polyclonal antibody (Cat # PAB24511) shows strong nuclear positivity in glandular cells at 1:20-1:50 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.
Using HNRNPAB polyclonal antibody (Cat # PAB24511). -
Gene Info — HNRNPAB
Entrez GeneID
3182Protein Accession#
Q99729Gene Name
HNRNPAB
Gene Alias
ABBP1, FLJ40338, HNRPAB
Gene Description
heterogeneous nuclear ribonucleoprotein A/B
Omim ID
602688Gene Ontology
HyperlinkGene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
apobec-1 binding protein 1|apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1|hnRNP type A/B protein
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