Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with ALDH1A3 polyclonal antibody (Cat # PAB24490) at 1:250-1:500 dilution.
Immunohistochemical staining of human prostate with ALDH1A3 polyclonal antibody (Cat # PAB24490) shows strong cytoplasmic positivity in glandular cells at 1:20-1:50 dilution.
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form. [provided by RefSeq