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Last updated: 2016/12/4
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BIK polyclonal antibody

  • Catalog # : PAB2449
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BIK.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BIK.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • The BIK polyclonal antibody (Cat # PAB2449) is used in Western blot to detect BIK in mouse brain tissue lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the BIK polyclonal antibody (Cat # PAB2449) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 638
  • Protein Accession#:
  • NP_001188;Q13323
  • Gene Name:
  • BIK
  • Gene Alias:
  • BIP1,BP4,NBK
  • Gene Description:
  • BCL2-interacting killer (apoptosis-inducing)
  • Gene Summary:
  • The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK. [provided by RefSeq
  • Other Designations:
  • BCL2-interacting killer,OTTHUMP00000028974,apoptosis-inducing NBK
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