ALG3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant ALG3.
Immunogen
Recombinant protein corresponding to amino acids of human ALG3.
Sequence
IDWKAYMAEVEGVINGTYDYTQLQGDTGPLVYPAGFVYIFMGLYYATSRGTDIR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with ALG3 polyclonal antibody (Cat # PAB24386) shows distinct cytoplasmic positivity in cells in tubules at 1:50-1:200 dilution. -
Gene Info — ALG3
Entrez GeneID
10195Protein Accession#
Q92685Gene Name
ALG3
Gene Alias
CDGS4, D16Ertd36e, NOT56L, Not56
Gene Description
asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ALG3 family. The encoded protein catalyses the addition of the first dol-P-Man derived mannose in an alpha 1,3 linkage to Man5GlcNAc2-PP-Dol. Defects in this gene have been associated with congenital disorder of glycosylation type Id (CDG-Id) characterized by abnormal N-glycosylation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
Not56-like protein|alpha-1,3-mannosyltransferase ALG3|asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)|asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase)|carbohydrate deficient glycopro
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Interactome
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Pathway
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