MFSD8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant MFSD8.
Immunogen
Recombinant protein corresponding to amino acids of human MFSD8.
Sequence
MAGLRNESEQEPLLGDTPGSREWDILETEEHYKSRWR
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of Lane 1: Negative control (vector only transfected HEK293T lysate).
Lane 2: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells with MFSD8 polyclonal antibody (Cat # PAB24363).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human kidney with MFSD8 polyclonal antibody (Cat # PAB24363) shows distinct cytoplasmic and membranous positivity in cells in tubules at 1:50-1:200 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-251 MG with MFSD8 polyclonal antibody (Cat # PAB24363) at 1-4 ug/mL dilution shows positivity in nucleus but not nucleoli and vesicles. -
Gene Info — MFSD8
Entrez GeneID
256471Protein Accession#
Q8NHS3Gene Name
MFSD8
Gene Alias
CLN7, MGC33302
Gene Description
major facilitator superfamily domain containing 8
Gene Ontology
HyperlinkGene Summary
This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq
Other Designations
ceroid-lipofuscinosis, neuronal 7, late infantile
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Interactome
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Pathway
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