NOC2L polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NOC2L.
Immunogen
Recombinant protein corresponding to amino acids of human NOC2L.
Sequence
LTVDEFLASGFDSESESESENSPQAETREAREAARSPDKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDS
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:200-1:500)
Western Blot (1:250-1:500)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with NOC2L polyclonal antibody (Cat # PAB24311) at 1:250-1:500 dilution.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human cerebellum with NOC2L polyclonal antibody (Cat # PAB24311) shows strong nucleolar positivity in Purkinje cells at 1:200-1:500 dilution.Immunofluorescence
Immunofluorescent staining of human cell line U-2 OS with NOC2L polyclonal antibody (Cat # PAB24311) at 1-4 ug/mL dilution shows positivity in nucleoli. -
Gene Info — NOC2L
Entrez GeneID
26155Protein Accession#
Q9Y3T9Gene Name
NOC2L
Gene Alias
DKFZp564C186, FLJ35172, NIR
Gene Description
nucleolar complex associated 2 homolog (S. cerevisiae)
Omim ID
610770Gene Ontology
HyperlinkGene Summary
Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT) (Hublitz et al., 2005 [PubMed 16322561]).[supplied by OMIM
Other Designations
OTTHUMP00000038432|novel INHAT (inhibitor of histone acetyltransferase) repressor|nucleolar complex associated 2 homolog
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Interactome
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