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Last updated: 2017/8/13
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SUMO4 polyclonal antibody

  • Catalog # : PAB2430
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SUMO4 (V55 Mutant).
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to human SUMO4 (V55 Mutant).
  • Sequence:
  • CEPRGLS(V)KQIRFRFG
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • SUMO4 (V55 Mutant)
  • Form:
  • Liquid
  • Purification:
  • Ammonium sulfate precipitation
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of SUMO4 polyclonal antibody (Cat # PAB2430) in HepG2 cell line lysate (35 ug/lane). SUMO4 mutant (arrow) was detected using the purified polyclonal antibody.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the SUMO4 polyclonal antibody (Cat # PAB2430) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • SUMO4
  • Gene Alias:
  • IDDM5,SMT3H4,SUMO-4,dJ281H8.4
  • Gene Description:
  • SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
  • Gene Summary:
  • This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017390,SMT3 suppressor of mif two 3 homolog 2,SMT3 suppressor of mif two 3 homolog 4,small ubiquitin-like modifier 4 protein,small ubiquitin-like protein 4
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