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Last updated: 2016/12/4
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SENP8 polyclonal antibody

  • Catalog # : PAB2423
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SENP8.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SENP8.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of SENP8 polyclonal antibody (Cat # PAB2423) in mouse spleen lysate. SENP8 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Protein Accession#:
  • NP_660205;Q96LD8
  • Gene Name:
  • SENP8
  • Gene Alias:
  • DEN1,HsT17512,NEDP1,PRSC2
  • Gene Description:
  • SUMO/sentrin specific peptidase family member 8
  • Gene Summary:
  • NEDD8 (MIM 603171) is a ubiquitin-like protein that becomes conjugated to the cullin (see CUL1; MIM 603134) subunit of several ubiquitin ligases. This conjugation, called neddylation, is required for optimal ubiquitin ligase activity. NEDD8-specific deneddylases, such as NEDP1, or DEN1, are required to process the NEDD8 propeptide at a C-terminal diglycine motif and to remove NEDD8 from cullins (Gan-Erdene et al., 2003 [PubMed 12759363]).[supplied by OMIM
  • Other Designations:
  • NEDD8-specific protease 1,SUMO/sentrin specific protease family member 8,deneddylase 1,protease, cysteine, 2 (NEDD8 specific),sentrin/SUMO-specific protease SENP8
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