SENP7 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SENP7.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human SENP7.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SENP7 polyclonal antibody (Cat # PAB2421) in mouse kidney tissue lysate (35 ug/lane). SENP7 (arrow) was detected using the purified polyclonal antibody. -
Gene Info — SENP7
Entrez GeneID
57337Protein Accession#
NP_065705;Q9BQF6Gene Name
SENP7
Gene Alias
KIAA1707, MGC157730
Gene Description
SUMO1/sentrin specific peptidase 7
Gene Ontology
HyperlinkGene Summary
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM
Other Designations
SUMO1/sentrin specific protease 7|sentrin/SUMO-specific protease|sentrin/SUMO-specific protease 7
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Interactome
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Publication Reference
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Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A.
Genome Research 2001 Mar; 11(3):422.
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Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O.
DNA Research 2000 Dec; 7(6):347.
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Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
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